Research Type: Plastics Europe
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Microplastic risk assessment and model development: Framework development and risk assessment model, upgrade and maintenance
Researchers / Institutional Affiliations Timeline Additional information Working Package 4 (risk assessment and model development) will use data from Working Packages 2 (exposure assessment) and 3 (hazard assessment). This research is applying an innovative approach to risk assessment that combines traditional in vivo-based approach with elements from next-generation alternative techniques. Professional Presentations N/A Published Papers… Read more
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Microplastic risk assessment and model development: Hazard assessment: General, systemic, ex vivo and in vivo toxicities
Researchers / Institutional Affiliations Timeline Additional information Working Package 3 includes an investigation of the level of i) general toxicity in cell culture; ii) systemic toxicity in cell culture; iii) toxicity in tissues (including a gastrointestinal simulator and a liver model); and toxicity at the organism level. Professional Presentations N/A Published Papers N/A Read more
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Microplastic risk assessment and model development: Exposure assessment: In silico model, transfer across barriers, in vivo tracking, human stool study
Researchers / Institutional Affiliations Timeline Funding Source Plastics Europe, Task 2.i. co-funded by Cefic-LRI (as project B24) Additional information The objective of Working Package 2 is to confirm and track the presence of microplastics in thehuman body. There is a focus on: an in silico human exposure computer model, being built incollaboration with Cefic-LRI project… Read more
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Microplastic risk assessment and model development: Production and analytical models: Milling, labeling, characterization and baseline testing
Researchers / Institutional Affiliations Timeline Q2 2022 to Q3 2024 (milling, labeling and characterization), Q3 to Q4 2024 (baseline testing) Additional information Ingestion and inhalation are hypothesized to be the main routes of exposure of humans to microplastics. This project focuses on ingestion. Microplastics will be prepared by the micronization of commercial-grade forms of examples… Read more