Microplastics

Microplastics

Microplastic risk assessment and model development: Hazard assessment: General, systemic, ex vivo and in vivo toxicities

This is also part of the Plastics Europe Brigid research project to assess potential risks to human health due to microplastic exposure via ingestion. Working Package 3 involves a hazard assessment at the levels of cells, tissues and organisms. The objective is to confirm and quantify whether the presence of microplastics in the body poses a hazard to human health.

Organized by Plastics Europe

Researchers / Institutional Affiliations

  • Cells: General toxicity
    Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek (TNO; The Netherlands)
  • Cells: Systemic toxicity
    TBD
  • Tissues: Ex vivo toxicity
    Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek (TNO; The Netherlands) The TIM Company (The Netherlands)
  • Organisms: In vivo toxicity
    TBD

Timeline

  • Cells: General toxicity: Q1 to Q3 2025
  • Cells: Systemic toxicity: Q3 2025 to Q4 2026
  • Tissues: Ex vivo toxicity: Q4 2025 to Q1 2026
  • Organisms: In vivo toxicity: Q1 to Q2 2025

Additional information

Working Package 3 includes an investigation of the level of i) general toxicity in cell culture; ii) systemic toxicity in cell culture; iii) toxicity in tissues (including a gastrointestinal simulator and a liver model); and toxicity at the organism level.

Professional Presentations

N/A

Published Papers

N/A